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模型用于预测西布拉明治疗肥胖症的影响

Sergey D Danilov1, Georgiy A Matveev1, Alina Yu Babenko1

  • 1Laboratory of Prediabetes and Metabolic Disorders, WCRC "Centre for Personalized Medicine", Almazov National Medical Research Centre, Saint Petersburg 197341, Russia.

Journal of personalized medicine
|August 29, 2024
PubMed
概括

这项研究开发了一个数据驱动的模型来预测患者对减肥西布拉明的反应. 该模型在3个月后达到71%的准确性,在6个月后达到80%,有助于个性化的肥胖治疗决策.

关键词:
沙普利的数据估值估值.这是XGBoost分类.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖预测模型 预测模型这种药物是西布特拉胺 (sibutramine).

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Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
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