皮肤冠状动脉干预中右与左辐射接入的比较分析:对静音脑缺血的影响
Abdulkadir Kara1, Korhan Soylu2, Ufuk Yildirim2
1Department of Cardiology, Elbistan State Hospital, 46300 Kahramanmaraş, Turkey.
Medicina (Kaunas, Lithuania)
|August 29, 2024
概括
穿皮冠状动脉干预 (PCI) 期间的右侧透射通道与左侧透射通道相比,增加了静音脑缺血 (SCI) 的风险. 吸烟和较低的射出分数也是导致SCI的重要因素.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 干预心脏病学 干预心脏病学
背景情况:
- 沉默性脑缺血症 (SCI) 是一种可以通过生化标志物或成像检测到的亚临床疾病.
- 了解皮肤冠状动脉干预 (PCI) 期间SCI的风险因素对于患者的治疗结果至关重要.
研究的目的:
- 为了比较PCI的右和左跨辐射接入之间的SCI发病率.
- 确定影响PCI后SCI发展的因素.
主要方法:
- 一项前性研究,对197名通过跨辐射接入接受PCI的患者进行了研究.
- 患者按右侧或左侧辐射动脉的通道分组.
- 在手术前和后测量了神经特异性酶 (NSE) 水平;SCI定义为NSE>20 ng/dL.
主要成果:
- 在197名患者中,SCI发生在60名患者中 (30.5%).
- 在右半径组 (37.4%) 与左半径组 (23.5%) (p=0.032) 中,SCI的发生率更高.
- SCI的独立预测因素包括右半径接触,吸烟和较低的射出分数.
结论:
- 与左侧透射接入相比,右侧透射接入与PCI后SCI风险明显更高.
- 吸烟,关节下动脉扭曲,HbA1c升高和射出分数减少等因素与SCI风险增加有关.
- 程序访问地点和患者特异性因素影响PCI后静音脑缺血的发生.
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