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在Roux-en-Y胃绕道术后的GERD:患病率和风险因素分析
Matas Pažusis1, Gabrielė Gerasimovič1, Rūta Petereit2
1Department of Surgery, Medical Academy, Lithuanian University of Health Science, 44307 Kaunas, Lithuania.
Medicina (Kaunas, Lithuania)
|August 29, 2024
概括
胃食道逆流性疾病 (GERD) 可以在Roux-en-Y胃旁路术 (RYGB) 后持续或发展,在12年后影响23.8%的患者. 重量增加和腹是手术后发展GERD的关键风险因素.
科学领域:
- 腹部外科 腹部外科
- 胃肠病学 胃肠病学
- 肥胖医学 肥胖医学
背景情况:
- 胃食道逆流性疾病 (GERD) 的患病率在肥胖个体中正在上升.
- 鲁克斯-en-Y胃绕道 (RYGB) 是有效的肥胖和GERD管理.
- 持续性或新发性GERD在一些RYGB后的患者中发生.
研究的目的:
- 为了确定GERD的患病率,在RYGB后12年.
- 在RYGB之后识别与GERD相关的风险因素.
主要方法:
- 对126名RYGB患者进行了前性研究,对其进行了12年的随访.
- 评估GERD症状,体重变化以及验证的问卷 (GERD-HRQL,TFEQ-18,GSRS).
- 多变量分析以确定术后GERD的预测因素.
主要成果:
- 手术后的GERD在23.8%的患者中存在 (12%持久,18% de novo).
- GERD-HRQL得分显著下降,但GSRS腹和消化不良得分增加.
- 重量恢复 (%WR) >11及更高的GSRS腹得分预测RYGB后的GERD.
结论:
- RYGB有效控制了GERD,但23.8%的患者在12年后经历了持续性或新发性GERD.
- GERD后RYGB的独立风险因素包括体重恢复和GSRS腹得分.
- 需要进一步研究这些风险因素的RYGB患者对GERD的管理.
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