局部过敏性鼻炎-对过敏学和耳鼻喉学合作的挑战 (范围审查)
Ovidiu Berghi1, Mihai Dumitru2, Romica Cergan3
1Allergology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Life (Basel, Switzerland)
|August 29, 2024
概括
局部过敏性鼻炎 (LAR) 是一种过敏性鼻炎的亚型,经常被误诊. 本综述涵盖了诊断,生活质量和治疗方法,如LAR的免疫疗法.
科学领域:
- 过敏学 过敏学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 局部过敏性鼻炎 (LAR) 是过敏性鼻炎 (AR) 的一个独特的亚型.
- 它影响了以前被诊断患有慢性非过敏性鼻炎的患者.
- 症状包括鼻,打喷和由过敏原引发的鼻.
研究的目的:
- 审查当前关于局部过敏性鼻炎 (LAR) 的证据.
- 突出LAR的诊断挑战和治疗选择.
主要方法:
- 开放访问PubMed文献的范围审查.
- 分析诊断方法,包括鼻腔过敏原挑战,局部IgE,基细胞激活测试 (BAT) 和鼻腔细胞学.
- 对治疗策略和生活质量影响的审查.
主要成果:
- 标准的AR测试 (皮肤刺伤,血清IgE) 在LAR中通常是负面的.
- 专门的测试对于准确的LAR诊断至关重要.
- LAR显著影响生活质量,与AR相当.
- 治疗选择反映了AR:避免过敏原,药物治疗和免疫治疗.
结论:
- 在标准的过敏检测之外,LAR需要专门的诊断方法.
- 存在有效的管理策略,包括过敏原免疫治疗.
- 需要进一步的研究来解决目前诊断和治疗的局限性.
相关概念视频
Allergic Reactions
27.3K
Overview
27.3K
Drugs Used in Lower Respiratory Disorders: Overview
362
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
362
Asthma: Pathogenesis and Management
374
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
374
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
251
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
251
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Chronic Pharyngitis
1.4K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.4K


