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Updated: Jun 14, 2025

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
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基于分子对接的FDA批准药物的虚拟查,使用西降解酶识别了新的酸剂

Rogelio Gómez-Escobedo1, Domingo Méndez-Álvarez2, Citlali Vázquez3

  • 1Departamento de Parasitología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México 07738, Mexico.

Molecules (Basel, Switzerland)
|August 29, 2024
PubMed
概括

经过重新设计的FDA批准的药物显示出对夏加斯病的有希望. 迪戈辛,阿伦德罗纳酸,流动和二欧哥他胺显示出三酸性活性,这表明对Trypanosoma cruzi感染的联合疗法的潜力.

关键词:
查加斯病是查加斯病的一种疾病.药物 FDA 药物 FDA 药物分子对接的分子对接.重新定位重新定位.试巴诺氨酸减少酶的作用.

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