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合成SNAC酸盐和对Semaglutide口服生物可用性的影响

Tovi Shapira-Furman1, Ayala Bar-Hai1, Amnon Hoffman1

  • 1Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.

Molecules (Basel, Switzerland)
|August 29, 2024
PubMed
概括

研究人员开发了新的N-[8-(2-基) 氨基]酸 (SNAC) 酸盐,以增强口服药物的吸收. 这些新的SNAC盐有望改善塞马格卢提德的输送,可能为注射剂提供口服替代品.

关键词:
在SNAC中,SNAC是SNAC.醇是一种醇.盐的合成盐的合成.塞马格卢提德 (semaglutide) 是一种可怕的药物.

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