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基于酸盐的内牙密封剂的抗生物膜有效性

Matilde Ruiz-Linares^1,2, Vsevolod Fedoseev¹, Carmen Solana^1,2

¹Department of Stomatology, University of Granada, 18071 Granada, Spain.

Materials (Basel, Switzerland)

|August 29, 2024

概括

基于酸的内牙密封剂在六周内证明了对生物膜的抗菌活性增加,长期表现优于环氧树脂密封剂.

科学领域:

牙周内科医院牙周内科医院牙周内科医院
微生物学微生物学
生物材料科学生物材料科学

背景情况:

具有持续抗微生物特性的内密封剂可以提高治疗成功率.
根性牙上的多微生物生物膜对内牙治疗构成了挑战.

研究的目的:

评估两种基于酸盐 (CS) 的密封剂 (AH Plus Bioceramic,BioRoot RCS) 对成熟的多微生物生物膜的长期抗菌疗效.
为了比较基于CS的密封剂与基于环氧树脂的密封剂 (AH Plus Jet) 的抗菌活性,随着时间的推移.

主要方法:

直接接触试验评估1周和6周后的密封剂抗菌活性.
使用腺三酸盐 (ATP) 试验和流细胞计 (FC) 的细胞活力评估.
统计分析包括Welch校正的ANOVA,Games-Howell,Duncan和Student的t测试.

主要成果:

以环氧树脂为基础的密封剂在一周后显示出优异的结果.
这两种基于CS的密封剂在6周后显著增加了抗菌疗效.
基于CS的密封剂显示出强大的长期抗微生物活性对生物膜.

结论:

基于酸的密封剂具有重要的长期抗微生物特性,适用于内牙科应用.
CS密封剂的持续抗菌作用有助于提高其改善内牙治疗结果的潜力.

关键词:

在AH Plus生物陶中使用.这是一架AH Plus Jet飞机.这是BioRoot的RCS.生物膜是一种生物膜.长期的抗微生物活性.

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