基于细菌的饮食三种菌株益生菌补充改善了断奶猪的表现,免疫功能,肠道形态和微生物群落
Lei Xue1, Shenfei Long1, Bo Cheng1
1State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Microorganisms
|August 29, 2024
概括
三重菌株Bacillus益生菌SOLVENS (SLV) 改善了小猪生长和免疫力. 补充SLV增强了平均每日增益,血清免疫球蛋白水平和肠道健康,这表明它减少了断奶压力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 益生菌被用作抗生素替代品,以获得动物健康的好处.
- 多菌株Bacillus益生菌对小猪的作用研究不足.
- 索尔文斯 (SLV) 是一种新型的三重菌株细菌益生菌.
研究的目的:
- 评估SLV对小猪表现,免疫力和肠道健康的影响.
- 为了研究SLV对断奶小猪肠道微生物群体的影响.
主要方法:
- 480只被奶的小猪被食了基础饮食,用0,200或400毫克/公斤的SLV进行了31天.
- 分析了生长性能,血清免疫参数 (IgA,IgG,Haptoglobin,CRP),肠道形态和基因表达.
- 随机的完整块设计,每次处理有20次复制.
主要成果:
- 400 mg/kg SLV 组在第二阶段显示平均每日增益 (ADG) 增加,并倾向于改善整体ADG.
- 服用SLV补充剂改善了料转换率,提高了血清免疫球蛋白A,免疫球蛋白G和平分球蛋白水平.
- SLV增加了头毛的高度和阴茎密室的深度,增加了杯状细胞数量,并调节了免疫基因表达 (下调的IL-4,TNF-α;上调的奥克卢丁).
结论:
- 补充SOLVENS (SLV) 有积极影响小猪生长性能和免疫反应.
- SLV改善了肠道形态和屏障功能,可能通过减轻免疫反应和减少断奶压力.
- 这种三种菌株的Bacillus益生菌显示出提高小猪健康和生产力的潜力.
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