保加利亚感染性内心炎的趋势:特征和结果,17年,单一中心经验
Bistra Dobreva-Yatseva1, Fedya Nikolov1, Ralitsa Raycheva2
1Section of Cardiology Cardiology Clinic, First Department of Internal Medicine, Faculty of Medicine, Medical University-Plovdiv, UMBAL "St. Georgi" EAD, 4000 Plovdiv, Bulgaria.
Microorganisms
|August 29, 2024
概括
保加利亚的传染性内心炎显示了老龄化的患者群体,并患有更多的并发病. 尽管风险因素发生了变化,但这种严重的心脏感染的30天死亡率仍然很高.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 传染性内心炎 (IE) 带来了诊断和治疗方面的挑战,死亡率高.
- 最近关于保加利亚IE趋势的数据有限,需要更新的流行病学见解.
研究的目的:
- 分析2005-2015年至2016-2021年期间保加利亚IE流行病学和临床特征的变化.
- 为了确定患者人口统计,并发症和IE的致病因子的变化.
主要方法:
- 在2005年至2021年期间,对270名被诊断患有IE的患者进行了回顾性单一中心研究.
- 两个不同的时间段之间的患者特征比较:2005-2015年 (n=119) 和2016-2021年 (n=151).
主要成果:
- 患者群体显著衰老,伴随着慢性病,冠状动脉疾病和心房动等并发病的患病率增加.
- 在后期观察到喷射分数的显著下降.
- 葡萄球菌物种是最常见的发现病原体 (33.3%),30天死亡率为24.8%.
结论:
- 在保加利亚,传染性内心炎的特征已经演变,其特点是人口老龄化和伴随性疾病负担增加.
- 葡萄球菌 spp. 葡萄球菌 spp. 仍然是占主导地位的病原体.
- 对IE的30天高死亡率仍然是一个重大的公共卫生问题.
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