功能性腹部膨胀和肠道微生物群:一个更新
Salvatore Crucillà1, Federico Caldart1, Marco Michelon2
1Gastroenterology B Unit, Pancreas Center, University of Verona, 37134 Verona, Italy.
Microorganisms
|August 29, 2024
概括
恢复肠道微生物群平衡是管理功能性腹部膨胀和膨胀 (FAB/FAD) 的关键. 像益生菌,益生菌和抗生素这样的向疗法显示出缓解症状的希望.
科学领域:
- 胃肠病学 胃肠病学
- 微生物组研究 微生物组研究
- 肠-大脑相互作用
背景情况:
- 功能性腹部膨胀和膨胀 (FAB/FAD) 是常见的肠脑相互作用障碍.
- 它们复杂的病理生理学涉及肠道微生物群的不平衡.
- 目前针对FAB/FAD的治疗方法仍然是一个临床挑战.
研究的目的:
- 审查目前关于FAB/FAD的证据,重点关注肠道微生物群的作用.
- 探索微生物群调制策略在管理FAB/FAD方面的潜力.
主要方法:
- 在2023年10月,对英语编辑的研究进行了叙事审查.
- 在Medline,PubMed和Embase数据库中进行文献搜索.
- 包括RCT,横截面,队列和病例控制研究.
主要成果:
- 选择了12项研究,主要是关联刺激性肠综合征 (IBS) 和微生物群.
- 恢复平衡的微生物组是FAB/FAD管理中最有前途的策略.
- 益生菌,益生菌,利法西明和饮食改变可能会减轻症状.
结论:
- 针对性肠道微生物群的干预措施 (益生菌,益生菌,抗生素) 对FAB/FAD至关重要.
- 了解肠道微生物群-FAB/FAD关系对于有效的治疗开发至关重要.
- 需要进一步的研究来阐明FAB/FAD中的特定微生物作用.
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