怀孕期间和之后的认知功能和1型糖尿病的一年产后:一项纵向研究
Marina Ivanisevic1, Vesna Elvedji Gasparovic1, Mislav Herman1
1Department of Obstetrics and Gynecology, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Nutrients
|August 29, 2024
概括
患有1型糖尿病 (T1DM) 的女性的认知功能在怀孕期间和之后受到负面影响. 较高的BMI和瘦素水平与这个人群中较差的认知结果有关.
科学领域:
- 内分泌学 在内分泌学.
- 神经科学是一个神经科学.
- 生殖医学 生殖医学
背景情况:
- 1型糖尿病 (T1DM) 在怀孕期间会带来独特的挑战.
- 孕妇的健康,包括认知功能,对于怀孕的结果至关重要.
- T1DM,怀孕和认知健康之间的相互作用需要进一步调查.
研究的目的:
- 为了比较怀孕期间和怀孕后T1DM妇女的认知功能.
- 为了评估分娩后一年的认知变化.
- 调查素和体重指数 (BMI) 对这一队列认知功能的影响.
主要方法:
- 对64名患有T1DM的孕妇进行了前性纵向队列研究.
- 在多个时间点使用综合电池评估认知功能:第一季度,分娩后立即和分娩后的一年.
- 认知领域的评估包括推理,记忆,注意力,协调和感知.
主要成果:
- 在怀孕妇女中观察到认知功能,记忆和推理能力下降的风险增加,BMI≥30kg/m2.
- 较低的整体认知功能和记忆与明显更高的勒丁度相关.
- 认知能力下降,特别是在怀孕期间和产后早期的推理和注意力方面.
结论:
- 在怀孕和产后期间,T1DM患者的认知功能,特别是推理和注意力受到不利影响.
- 体重指数和瘦素水平的升高与T1DM孕妇认知结果的恶化有关.
- 这些发现强调了代谢和荷尔蒙因素对母亲认知健康的重要性.
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