关于成人免疫计划更广泛价值的结构化叙事文献审查
Hania El Banhawi1, Eleanor Bell1, Margherita Neri1
1Office of Health Economics, London SE1 2HD, UK.
Vaccines
|August 29, 2024
概括
成人免疫计划为健康和医疗保健系统提供了重要的价值. 然而,关于经济影响和护理人员福祉等更广泛的社会利益的证据仍然有限,可能导致计划价值被低估.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 疫苗可预防的疾病构成了越来越大的负担,特别是随着人口老龄化.
- 了解成人免疫的综合价值对于基于证据的决策至关重要.
研究的目的:
- 审查和绘制成年人免疫计划对流感,肺炎球菌病,RSV和疹病毒 (HZ) 的价值的证据.
- 评估十个不同国家的不同价值元素的证据可用性.
主要方法:
- 从2017-2023年对证据的结构化文献综述.
- 利用现有的框架来评估特定疫苗和国家的价值元素.
- 开发了矩阵来证明证实的价值.
主要成果:
- 对于成年人免疫计划,存在大量的证据基础,尽管它因价值元素和疫苗而异.
- 生活质量,死亡率效益和医疗保健成本抵消得到了充分证据.
- 关于更广泛的社会价值因素 (例如,传播,股权,抗药性抵抗预防) 的证据是可变的;没有确定宏观经济影响和护理人员影响.
结论:
- 成人免疫计划显然为人口健康和卫生系统提供了显著的价值.
- 文献中更广泛的价值元素的代表性不足,有可能低估这些计划,并可能导致不理想的政策决策.
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