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Updated: Jun 14, 2025

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儿童癌症免疫检查点抑制剂:它仍然是一个局吗?

Tang-Her Jaing1, Yi-Lun Wang1, Chia-Chi Chiu2

  • 1Division of Hematology and Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 33315, Taiwan, China.

Pharmaceuticals (Basel, Switzerland)
|August 29, 2024
PubMed
概括

免疫检查点抑制剂 (ICI) 在大多数儿科癌症中表现出有限的成功,原因是新抗原水平较低. 然而,特定的子集,如高突变和SMARCB1缺陷癌症,对ICI疗法表现出有前途的反应.

关键词:
在SMARCB1中缺少.过度突变的过度突变的免疫检查点抑制剂 免疫检查点抑制剂儿科癌症 儿科癌症

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