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使用质量设计原则将Xalkori儿科多颗粒物产品商业化

Jeremy Bartlett1, Natalie Culver1, Xiang Zhang1

  • 1Pfizer, Eastern Point Road, Groton, CT 06340, USA.

Pharmaceutics
|August 29, 2024
PubMed
概括

通过使用质量设计原则开发了crizotinib (Xalkori) 的新型儿科剂型. 这种节约材料的方法确保了在儿科患者灵活剂量的特殊含量统一性.

关键词:
在商业化,商业化.实验的设计 (DOE)剂量灵活性 剂量灵活性脂质多颗粒物是一种多颗粒物.材料节约的方法.化喷雾凝结 (MSC) 是一种这些微球是微球.多颗粒物是一种多颗粒物.儿科 儿科 儿科 儿科颗粒 颗粒 颗粒过程优化优化过程优化设计中的质量 (QbD)味道掩饰是一种口味掩饰.一致性是一致性.容量测量剂量仪 容量测量剂量仪

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