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Updated: Jun 14, 2025

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
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热挤出对格利本克拉米德物理和化学状态以及溶解行为的影响:用三种聚合物混合矩阵的案例研究

Nina Zupan1,2, Ines Yous1, Florence Danede2

  • 1Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.

Pharmaceutics
|August 29, 2024
PubMed
概括

热挤出 (HME) 可以降解甘胺到杂质A.聚合物混合物显著影响药物的稳定性,并控制持续的药物释放超过24小时.

关键词:
降解降解降解降解降解.基甲胺的使用方法热挤出方式固体分散的散发方式持续释放药物的持续释放药物三元混合物是一种三元混合物.

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