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大麻提取程序对大麻素和类成分的影响

Francisco T Chacon¹, Wesley M Raup-Konsavage², Kent E Vrana²

¹Intercollege Graduate Degree Program in Plant Biology, Pennsylvania State University, University Park, State College, PA 16802, USA.

Plants (Basel, Switzerland)

|August 29, 2024

概括

不同的麻提取方法产生独特的植物化学特征. 水蒸在烯中表现出色,而超临界CO2提取则最大限度地提高了CBD等大麻素,影响了产品的有效性和安全性.

科学领域:

植物化学植物化学
分析化学分析化学
药理学是指药理学,即药理学是指药理学.

背景情况:

大麻 (Cannabis sativa L.) 的植物化学物质对研究和消费有价值.
常见的提取方法包括超临界CO2,水蒸和乙醇提取.
这些方法可能会对最终的植物化学成分产生不同的影响,影响产品质量和效果.

研究的目的:

通过三种主要商业方法获得的麻提取物的大麻素和烯概况进行比较.
分析超临界CO2,水蒸和乙醇提取所产生的化学成分.
了解提取技术如何影响大麻的化学成分.

主要方法:

来自CBD/CBG主导品种的麻花采用超临界CO2,水蒸和乙醇提取.
使用气体染色学质谱法 (GC-MS) 分析了烯含量.
使用液体染色学-质谱学/质谱学 (LC-MS/MS) 来量化大麻素含量.

主要成果:

水蒸提取物显示了最高的烯多样性和丰度,其中β-caryophyllene是最缩的.
超临界二氧化碳提取物产生了最多样和最丰富的大麻素,CBD含量在12.8-20.6毫克/克之间.
乙醇提取物含有最高水平的酸性大麻素,如CBDA (3.2-4.1 mg/g) 和最小的烯.

结论:

选择大麻提取方法显著影响了由此产生的大麻素和烯配置文件.
不同的提取工艺导致不同的化学成分,可能会影响大麻产品的有效性,耐受性和安全性.
了解这些差异对于优化大麻产品开发和应用至关重要.

关键词:

大麻素是一种大麻素.大麻大麻大麻大麻大麻大麻大麻大麻乙醇提取方法乙醇提取方法提取提取提取提取通过水蒸蒸的方式.这是一个超临界的超临界状态.它们是烯 (terpenes).

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