关于状细胞疾病并发症的编码定义的标准化:一个系统的文献审查
Paulette Negron Ericksen1, Firas Dabbous2, Rajrupa Ghosh2
1Pfizer Inc, New York, New York, USA.
Pharmacoepidemiology and drug safety
|August 29, 2024
概括
本综述确定了常见的状细胞疾病并发症及其诊断代码,用于现实世界的证据研究. 标准化这些准则将提高研究的准确性和透明度.
科学领域:
- 血液学 血液学 血液学
- 医疗信息学 医疗信息学
背景情况:
- 状细胞疾病 (SCD) 影响所有器官系统,导致复杂的并发症和并发症.
- 现实世界证据 (RWE) 研究需要标准化编码来准确分析SCD并发症.
研究的目的:
- 系统地审查和列出与SCD相关的并发症/并发症.
- 识别和编译用于这些并发症的RWE研究中的诊断代码.
主要方法:
- 在 MEDLINE 和 Embase (2016-2023) 进行了系统的文献搜索.
- 包括美国的SCD研究报告并发症和国际疾病分类,临床修改 (ICD-CM) 代码.
- 并发症和代码由经过认证的医学编码专家和血液学家审查.
主要成果:
- 1851项研究中,有39项符合纳入标准.
- 最常见的并发症:中风,急性胸部综合征,肺栓塞,静脉血栓塞,血管闭塞危机.
- 观察到编码异质性;在审查的文献中,ICD-9-CM代码比ICD-10-CM代码更常见.
结论:
- 鉴定到的编码变异凸显了在SCD研究中需要标准化诊断代码的需要.
- 这一审查为一致识别SCD并发症提供了基础,提高了透明度和可重复性.
- 建议为未来的研究工作进一步验证拟议的代码列表.
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