在新诊断的患者中,坚持使用医疗眼治疗
Joana Menino1, Pedro Camacho1,2,3, Andre Coelho1
1H&TRC- Health and Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saude, Instituto Politecnico de Lisboa, Lisbon, Portugal.
Medical hypothesis, discovery & innovation ophthalmology journal
|August 29, 2024
概括
近三分之一的青光眼患者在三年内停止抗青光眼治疗,风险是视力丧失. 监测持续性是控制青光眼的进展和预防失明的关键.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 药物经济学 药物经济学
背景情况:
- 停止抗玻璃眼癌治疗可能会导致玻璃眼癌的进展和不可逆转的失明.
- 识别患有停止治疗的高风险的患者对于有效的疾病管理至关重要.
- 在现实世界中,抗瘤治疗的持续性对于长期的疾病控制至关重要.
研究的目的:
- 为了评估抗光眼患者抗光眼治疗的现实世界持久性.
- 为了识别与停止抗葡萄糖瘤治疗相关的危险因素.
- 评估里斯本和泰戈斯河谷地区的初级医疗保健机构的治疗持续性.
主要方法:
- 对新使用抗白血病药物的处方记录进行了回顾性纵向研究 (2012-2013).
- 在3年内对2138名患者进行了随访,以评估治疗持续性.
- 持续性是指患者在1,2,3年内继续服用任何抗葡萄糖瘤药物的比例.
主要成果:
- 整体持久性从第一年91.9%下降到第三年67.3%.
- 老年患者 (≥65岁) 初始持续性较高,但随着时间的推移也呈现下降.
- 与组合疗法相比,初始单一治疗的患者表现出更高的持续率.
结论:
- 很大一部分患者停止抗白内障治疗,增加了白内障进展的风险.
- 定期对患者进行随访至关重要,以确保患者遵守治疗并预防视力丧失.
- 未来的研究应该利用健康信息系统探索坚持和持久性对眼结局的影响.
相关概念视频
Open Angle Glaucoma: Treatment
408
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
408
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454


