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患者对炎症性肠病治疗的偏好:使用离散选择实验进行全球偏好调查的协议开发
Elise Schoefs1, Séverine Vermeire2,3, Marc Ferrante2,3
1Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Frontiers in medicine
|August 29, 2024
概括
了解患者对炎症性肠病 (IBD) 治疗的偏好至关重要. 这项研究量化了IBD患者对疾病和治疗属性的优先考虑,以告知医疗保健决策.
科学领域:
- 胃肠病学和肝病学
- 医疗保健服务研究 医疗服务研究
- 患者报告的结果
背景情况:
- 炎症性肠病 (IBD) 的不断扩大的治疗领域需要了解患者的价值观.
- 目前和新兴的IBD治疗需要以患者为中心的评估.
- 对医疗保健专业人员,药物开发商,监管机构和付款人来说,洞察力至关重要.
研究的目的:
- 确定IBD治疗和与疾病相关的属性的相对偏好权重.
- 确定患者偏好如何根据特征不同 (偏好异质性).
主要方法:
- 一个强大的8步过程,由咨询委员会和患者的意见提供信息.
- 开发一个离散选择实验 (DCE) 调查,有14个属性和15个选择任务.
- 全球招募至少700名15种语言的IBD患者.
主要成果:
- 研究协议为偏好研究提供了一个透明的框架.
- 结果将阐明IBD患者优先考虑的关键疾病和治疗属性.
- 证据将突出不同患者子组的偏好差异.
结论:
- 这种患者偏好研究方案提供了宝贵的方法论见解.
- 这些发现将使药物开发,监管部门的批准和补偿与患者的需求保持一致.
- 该研究支持整个产品生命周期的以患者为中心的决策.
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