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系统地调查螺丝元件在连续湿颗粒处理中对螺丝元件的影响

Katharina Kiricenko1, Robin Meier2, Peter Kleinebudde1

  • 1Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute of Pharmaceutics and Biopharmaceutics, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

International journal of pharmaceutics: X
|August 29, 2024
PubMed
概括

双螺丝湿颗粒化 (TSG) 过程的优化是制药制造的关键. 螺丝配置显著影响颗粒性质和随后的平板,但TSG在设计中显示出强度.

关键词:
连续制造 连续制造制造设计实验的设计.螺丝的配置配置 螺丝配置双螺旋湿颗粒制造的双螺旋制造

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In Vitro Drug Dissolution: Compendial Testing Models I01:13

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Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
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