评估2型糖尿病患者的饮食酸负荷和心血管风险因素之间的关系:一个病例对照研究
1Faculty of Health Science, Department of Nutrition and Dietetics, Atılım University, Ankara, Türkiye.
Frontiers in nutrition
|August 29, 2024
概括
高潜在酸负荷 (PRAL) 饮食与2型糖尿病患者的高甘油三相关. 需要进一步的研究来证实饮食中的酸负载.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 心血管疾病研究研究
背景情况:
- 饮食中高含酸负载的饮食与代谢疾病有关.
- 在土耳其,对饮食中的酸性负荷和代谢疾病的研究有限.
- 2型糖尿病在全球和土耳其具有重大公共卫生挑战.
研究的目的:
- 研究2型糖尿病患者的饮食酸荷载和心血管疾病风险因素之间的关系.
- 评估潜在的酸负载 (PRAL) 和内源性净酸产量 (NEAP) 与心血管风险因素之间的关联.
主要方法:
- 一项涉及51名2型糖尿病患者和59名对照患者 (年龄在30-65岁之间) 的病例控制研究.
- 通过3天的食物消费记录来评估饮食摄入量,以计算PRAL和NEAP分数.
- 测量了心血管风险因素,包括血压,生化标志物,人体测量和身体组成.
主要成果:
- 在糖尿病组中,在较高的PRAL得分和高的甘油三水平 (TG) 之间发现了显著的积极关联 (OR,5.98;p=0.013).
- 在对照组 (OR,0.21;p=0.026) 中观察到PRAL和缩血压 (SBP) 之间的负相关性.
- 在这两组中,NEAP值和心血管风险因素之间没有发现显著的关联.
结论:
- 较高的潜在酸负荷 (PRAL) 与2型糖尿病患者的甘油三水平增加有关.
- 这项研究强调了饮食中的酸负荷与糖尿病中心血管风险因素之间的潜在联系.
- 建议进行进一步的纵向和干预研究以确定因果关系.
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