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Updated: Jun 14, 2025

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改变β1-上腺素受体N-终端单核酸变体的O-糖化调节受体处理和功能活动

Hanna E Tuhkanen1, Ilona J Haasiomäki1, Jarkko J Lackman1,2

  • 1Medical Research Center Oulu and Research Unit of Biomedicine and Internal Medicine, University of Oulu, Finland.

The FEBS journal
|August 29, 2024
PubMed
概括

在G蛋白合受体 (GPCRs) 中常见的遗传变异可以改变它们的功能. 这项研究表明,β-1上腺素受体 (β1AR) 中的N端单核酸多态 (SNPs) 影响其处理和信号传递,可能导致功能获取.

关键词:
G蛋白结合受体的受体与蛋白质结合的受体相结合.在O-glycosylation的过程中,蛋白质溶解加工是一种蛋白质溶解加工.单核酸多形态的单核酸多形态在β1 - 上腺素受体.

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