Dsr介导的硫氧化过程的进化历史和起源
Katherine M Klier1,2, Cody Martin1,3, Marguerite V Langwig1,2
1Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, United States.
The ISME journal
|August 29, 2024
概括
微生物在硫循环中利用异样硫酸盐还原酶 (Dsr). 这项研究表明,一些微生物,如SAR324,具有氧化和减少硫的基因,这表明与氧化硫的进化联系.
科学领域:
- 微生物学 微生物学
- 生物地质化学生物地质化学
- 进化生物学 进化生物学
背景情况:
- 微生物通过元素硫氧化和硫酸盐还原驱动硫循环.
- 分散硫酸盐还原酶 (Dsr) 催化这些过程,以减少或氧化方向起作用.
- 虽然有机体通常只执行一种途径,但有些人拥有两种途径的基因,表明复杂的DSR进化.
研究的目的:
- 调查候选属SAR324.4中DSR介导新陈代谢的生态和演变.
- 探索各种微生物类型中混合的还原性和氧化性DSR基因含量的影响.
- 为了了解DSR介导的硫氧化过程的进化起源.
主要方法:
- 对SAR324和其他类中的DSR基因含量的基因组分析.
- 对DsrAB序列的遗传学分析.
- 进行比较基因组学,以识别具有混合DSR途径的生物.
主要成果:
- 不同的SAR324菌株编码的基因为减少Dsr,氧化Dsr,或两者兼而有之.
- 具有还原性和氧化性DSR蛋白的生物很少见,只在少数族群中发现.
- DsrAB序列的遗传学位置表明,进化过渡向氧化Dsr代谢.
结论:
- 候选类型SAR324表现出多功能DSR新陈代谢,编码硫氧化和还原的基因.
- 在某些族群中,包括SAR324中,混合DSR基因含量的存在与硫氧化演变有关.
- 这些发现表明,具有混合DSR路径的生物体可能代表DSR介导的硫氧化演化的过渡阶段.
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