聚焦的外科期营养补充剂在接受脊柱融合手术的患者中减少了伤口并发症
Christopher J Como1,2,3, Joshua C Setliff1,2,3, Jonathan F Dalton1,2,3
1Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
Spine
|August 29, 2024
概括
在脊髓融合手术后的强化术后营养补充剂显著减少了伤口并发症和重复手术. 这种具有成本效益的策略通过减轻与营养不良相关的风险来改善患者的治疗结果.
科学领域:
- 整形外科手术 整形外科手术
- 外科手术的结果
- 营养科学 营养科学
背景情况:
- 营养状况不佳与手术后增加的死亡率,感染和伤口愈合并发症有关.
- 对于脊柱融合患者的特定营养干预措施的研究有限.
- 术后营养补充剂在减少手术风险方面显示出有前途.
研究的目的:
- 评估强化术后营养补充对伤口愈合并发症的影响.
- 评估营养支持对脊柱融合手术后患者结果的影响.
主要方法:
- 脊髓融合患者的回顾性队列研究 (2019-2022年).
- 对人口和营养数据的分析,包括前专辑蛋白 (PAB) 水平和术后饮食.
- 主要终点:伤口并发症;次要终点:奥斯韦斯特里残疾指数 (ODI) 和PROMIS身体健康 (PH) 评分.
主要成果:
- 接受补充饮食的患者明显减少了伤口并发症 (7%对21%,P=0.004) 和重复手术 (3%对11%,P=0.016).
- 两组之间没有观察到PROMIS PH或ODI得分的显著差异.
- 在没有补充剂的情况下,正常手术前PAB患者的并发症较多 (5%对18%,P=0.025).
结论:
- 手术后的营养补充剂是一种具有成本效益的方法,可以减少脊髓融合后的伤口并发症.
- 营养策略可以有效地减轻外科手术期间的风险,突出可修改的风险因素.
- 这种干预措施改善了经过脊髓融合的患者的外科治疗结果.
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