环境空气污染导致了中国的肺结核病
Zhongqi Li1,2, Qiao Liu2, Liang Chen3
1Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China.
Emerging microbes & infections
|August 29, 2024
概括
室外空气污染,包括SO2,NO2,PM2.5和CO,与增加结核病风险有关. 减少空气污染可能有助于降低全球结核病负担.
科学领域:
- 环境流行病学环境流行病学
- 公共卫生 公共卫生
- 呼吸系统药物 呼吸系统药物
背景情况:
- 关于室外空气污染和结核病风险的已发表的研究结果不一致.
- 差异可能是由于地理范围有限,暴露时间不同,以及先前研究中的各种统计方法.
研究的目的:
- 综合调查环境空气污染物与结核病风险之间的关联.
- 通过采用多省多城市时间序列设计来解决先前研究的局限性.
主要方法:
- 从2014年到2019年,在中国的67个地区/县进行了一项时间序列研究.
- 收集了新诊断的肺结核病例,空气污染物度 (SO2,NO2,PM10,PM2.5,CO) 和气象因素的数据.
- 用一个通用的添加模型来评估空气污染物和PTB风险之间的关系.
主要成果:
- 在研究期间,共报告了172,160例新的PTB病例.
- 增加的SO2,NO2,PM10,PM2.5和CO与增加的PTB风险有关,每个污染物报告的具体百分比增加和滞后时间.
- 例如,SO2的10μg/m3增加与PTB风险上升1.97% (滞后0周) 有关.
结论:
- 环境空气污染物与结核病风险有积极的相关性.
- 研究结果表明,减少室外空气污染物度可能是减轻结核病负担的策略,特别是在空气污染和结核病发病率高的地区.
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