Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

1.7K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
1.7K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

972
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
972
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

2.5K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
2.5K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

446
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
446
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

3.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.6K
Lobes of the Cerebrum01:22

Lobes of the Cerebrum

588
The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
588

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Hippocampal communication with the anterior olfactory nucleus is necessary for context-dependent odor memory.

Behavioral neuroscience·2026
Same author

The Infralimbic, but not the Prelimbic Cortex is needed for a Complex Olfactory Memory Task.

bioRxiv : the preprint server for biology·2024
Same author

The Retrosplenial Cortical Role in Delayed Spatial Alternation.

bioRxiv : the preprint server for biology·2024
Same author

A comparison of hippocampal and retrosplenial cortical spatial and contextual firing patterns.

Hippocampus·2024
Same author

Time Cells in the Retrosplenial Cortex.

bioRxiv : the preprint server for biology·2024
Same author

Effects of social context manipulation on dorsal and ventral hippocampal neuronal responses.

Hippocampus·2023

相关实验视频

Updated: Jun 14, 2025

Simultaneous Two-photon In Vivo Imaging of Synaptic Inputs and Postsynaptic Targets in the Mouse Retrosplenial Cortex
16:45

Simultaneous Two-photon In Vivo Imaging of Synaptic Inputs and Postsynaptic Targets in the Mouse Retrosplenial Cortex

Published on: March 13, 2016

11.5K

时间细胞在后皮层的时间细胞.

Dev Laxman Subramanian1, David M Smith1

  • 1Department of Psychology, Cornell University, Ithaca, New York, USA.

Hippocampus
|August 29, 2024
PubMed
概括

脑后皮层 (RSC) 神经元表现出时间细胞,这对于情节性记忆中的时间编码至关重要. 当记忆需求较高时,这些细胞更为普遍,并且更具任务特异性,支持RSC在记忆中的作用.

科学领域:

  • 神经科学是一个神经科学.
  • 认知神经科学 认知神经科学
  • 系统神经科学 系统神经科学

背景情况:

  • 脑后皮质 (RSC) 对于记忆至关重要,与海马相连,并参与情节性记忆.
  • 时间信息编码对于情节性记忆至关重要,在海马体中观察到时间细胞.
  • 虽然RSC病变会损害时间记忆,但在RSC中以前还没有发现时间细胞.

研究的目的:

  • 为了研究时间细胞在后皮层 (RSC) 的存在和特征.
  • 为了确定RSC时间细胞是否对不同行为任务的记忆需求敏感.
  • 评估RSC对情节性记忆中的时间编码的贡献.

主要方法:

  • 在审判间延期期间,从RSC重新分析了档案神经元发射数据.
  • 在阻塞交替任务 (高内存需求) 和cued T-迷宫任务 (低内存需求) 中对RSC活动进行比较.
  • 在RSC神经元中识别和描述时间细胞和响应停止时间场.

主要成果:

  • 时间单元在阻塞交替任务期间在RSC中普遍存在,区分试验类型.
  • RSC神经元表现出响应时间场,表明受抑制发射的时期.
  • 时间单元在cued T-迷宫任务中不那么普遍,也不那么有区别,这表明对记忆负载的敏感性.
关键词:
这是一种情节性记忆 (episodic memory).脑后大脑皮层 (retrosplenial cortex) 的一个部分.时间编码时间编码.时间上下文 时间上下文时间细胞时间细胞.

更多相关视频

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations
10:45

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations

Published on: June 14, 2020

7.4K
Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
09:45

Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex

Published on: March 28, 2012

15.6K

相关实验视频

Last Updated: Jun 14, 2025

Simultaneous Two-photon In Vivo Imaging of Synaptic Inputs and Postsynaptic Targets in the Mouse Retrosplenial Cortex
16:45

Simultaneous Two-photon In Vivo Imaging of Synaptic Inputs and Postsynaptic Targets in the Mouse Retrosplenial Cortex

Published on: March 13, 2016

11.5K
Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations
10:45

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations

Published on: June 14, 2020

7.4K
Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
09:45

Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex

Published on: March 28, 2012

15.6K

结论:

  • 时间编码是RSC神经活动的突出特征.
  • RSC 时间细胞对任务的记忆需求很敏感.
  • 这些发现支持RSC通过时间信息处理在情节性记忆中发挥重要作用.