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在日本患者中青少年发病的结脊髓炎的临床特征
Kenji Kishimoto1,2, Shuji Asai1, Mochihito Suzuki1
1Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Modern rheumatology
|August 29, 2024
概括
在日本患者中,青少年发病性化脊柱炎 (JoAS) 往往在背部,部或膝盖出现初始症状. 超过一半的JoAS患者最初被误诊为其他肌肉骨疾病.
科学领域:
- 类风湿病学 类风湿病学
- 儿科风湿病学 儿科风湿病学
- 临床研究 临床研究
背景情况:
- 青少年发病性性脊柱炎 (JoAS) 是一种慢性炎症性疾病,影响年轻人.
- 了解JoAS的早期临床表现对于及时诊断和管理至关重要.
- 日本JoAS患者数据对于了解特定种族的疾病模式至关重要.
研究的目的:
- 在一组日本患者中调查青少年发病性结脊柱炎 (JoAS) 的临床特征.
- 分析日本JoAS患者的初始症状和诊断进展.
- 为了确定JoAS早期常见的错误诊断.
主要方法:
- 在2004年1月至2023年5月期间诊断的17名日本JoAS患者的回顾性研究.
- 分析初始症状,包括轴关节和/或轴外关节疼痛.
- 对诊断途径和记录的初始诊断进行审查.
主要成果:
- 发病时的平均年龄为12.9岁,诊断时的平均年龄为19.6岁.
- 最初的症状最常发生在背部 (41.2%),部 (29.4%) 和膝盖 (29.4%).
- 超过一半 (52.9%) 的患者最初出现的症状仅限于额外轴关节,并且经常被误诊 (52.9%) 与其他肌肉骨疾病.
结论:
- 背部,部和膝盖是日本JoAS患者初始症状的常见部位.
- 显著比例的JoAS患者 (52.9%) 最初呈现出额外轴关节症状.
- 延迟诊断是常见的,超过一半的患者最初被误诊为JoAS以外的疾病.
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