内化艾滋病毒污名和病毒抑制:检查物质使用和社会支持的调解和适度作用
Timothy N Crawford1, Torsten B Neilands2, Lydia N Drumright3
1Wright State University, Dayton, Ohio.
AIDS (London, England)
|August 29, 2024
概括
内化艾滋病毒污名化恶化病毒非抑制通过抑郁症,药物使用和不良药物坚持恶化. 社会支持可能有所帮助,但需要更多的研究来改善艾滋病毒感染者的健康结果.
科学领域:
- 公共卫生 公共卫生
- 临床医学 临床医学
- 心理学 心理学 心理学
背景情况:
- 内化艾滋病毒污名是治疗坚持和健康结果的重要障碍.
- 了解这种耻辱影响的调解者对于有效的干预至关重要.
- 社会支持是一种潜在的保护因素,但它的调节作用需要研究.
研究的目的:
- 通过抑郁症状,酒精使用,非法药物使用和药物坚持来检查内部化艾滋病毒污名如何影响病毒非抑制.
- 调查社会支持是否能缓和这些间接影响.
- 找出将耻辱与艾滋病毒感染者健康状况较差的联系途径.
主要方法:
- 在美国 (2016-2019) 接受艾滋病毒治疗的9574名患者进行了长度观察性临床队列研究.
- 用结构方程建模 (SEM) 来测试间接影响.
- 调节调解分析检查了社会支持和内化艾滋病毒污名之间的相互作用.
主要成果:
- 内化艾滋病毒污名显著和间接影响病毒非抑制.
- 抑郁症状,非法药物使用和药物坚持作用于这种效应.
- 在酒精使用方面发现了耻辱和社会支持之间的相互作用,但没有观察到温和的调解.
结论:
- 内化艾滋病毒污名负面影响通过抑郁症,药物使用和药物坚持病毒抑制.
- 社会支持可能提供一些缓冲效应,这需要进一步研究.
- 针对这些媒介对于改善艾滋病毒感染者的健康和病毒抑制至关重要.
相关概念视频
Pulmonary Tuberculosis I
227
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
227
Stress and Mental Health
88
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
88
Sexually Transmitted Infections
286
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
286
Retrovirus Life Cycles
45.8K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.8K
Substance Use Disorders Affecting Sleep
163
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
163
Self-Help Support Groups
28
Self-help support groups are voluntary, community-based organizations that provide a platform for individuals with shared concerns to exchange support, insights, and practical strategies for coping with life challenges. Typically led by group members or paraprofessionals, these groups form a cornerstone of mental health care, especially in reaching populations that are underserved by traditional healthcare systems.
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
28


