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Updated: Jul 11, 2026

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基于双重质量标签的量化蛋白质组分析,对甲福明对卵巢癌细胞的抑制作用进行量化蛋白质组分析

Dongyue Wang1, Jingchen Wang2, Yingying Cui2

  • 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.

Journal of cancer research and therapeutics
|August 29, 2024
PubMed
概括

甲胺 (MET) 通过改变铁运输和线粒体功能,在卵巢癌中表现出抗瘤作用. 这项研究确定了关键的蛋白质变化,表明MET与代谢药物相结合可以增强癌症治疗.

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...