在日本,使用体积调节弧线疗法技术进行全身辐射的第一个临床经验
Yuki Nozawa1, Hideomi Yamashita, Subaru Sawayanagi
1Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Journal of cancer research and therapeutics
|August 29, 2024
概括
体积调节弧线疗法全身辐射 (VMAT-TBI) 提供了一个精确且不那么繁的放射治疗选择. 这种先进的技术在接受干细胞移植的白血病患者中成功实施.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 血液学 血液学 血液学
背景情况:
- 像VMAT这样的高精度放射治疗技术正在推进癌症治疗.
- 全身辐射 (TBI) 是干细胞移植协议的关键组成部分.
研究的目的:
- 报告我们机构首次临床实施全身辐射VMAT (VMAT-TBI).
- 评估VMAT-TBI在B细胞急性淋巴细胞白血病患者的可行性和特征.
主要方法:
- 卷度调节弧线疗法 (VMAT) 用于全身辐射 (TBI).
- 治疗计划包括两个分数,为计划目标体积提供4Gy.
- VMAT-TBI计划被分为上部和下部身体部分,并指定了特定的异中心.
主要成果:
- 在一个56岁的男性患者身上成功进行了VMAT-TBI,该患者正在接受与平分异性相关的外周血液干细胞移植的预治疗.
- 对于VMAT-TBI的总治疗时间约为55分钟.
- 治疗时间与传统的移动沙发技术相当.
结论:
- VMAT-TBI代表了一种可行的,准确的,潜在的不那么繁的全身辐射方法.
- 这种技术可能为需要TBI作为癌症治疗方案的一部分的患者提供显著的优势.
相关概念视频
Biological Effects of Radiation
15.4K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.4K
Absorption of Radiation
712
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
712
Radiological Investigation I: X-ray and CT
218
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
218
Radiological Investigation III: Pulmonary Angiogram and PET Scan
88
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
88


