设计一种氧类固醇脱酶,同时增强活性和热稳定性,以有效地生物合成乌尔索二氧化醇酸

Yuan Li1,2, Shu-Fang Li1,2, Lin Zhang1,2

  • 1Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.

概括

工程化基类固醇脱酶显示出提高稳定性和活性,用于高效的类固醇合成. 一种新的半理性方法与NAD激酶辅因子再生相结合,显著提高了生物转化过程的成本效益.

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