Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Chemical Synapses01:26

Chemical Synapses

8.8K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
8.8K
The Synapse02:47

The Synapse

124.6K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
124.6K
Overview of Synapses01:25

Overview of Synapses

2.2K
A synapse is a specialized structure where two neurons connect, allowing them to pass an electrical or chemical signal to another neuron. It is the point of communication between neurons. The term "synapse" is derived from the Greek word "synapsis," which means "conjunction." The entire process of neural communication revolves around the synapse. When activated, a neuron releases chemicals known as neurotransmitters into the synapse. These neurotransmitters cross the synapse and bind to...
2.2K
Synaptic Signaling01:09

Synaptic Signaling

5.5K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
5.5K
Excitatory and Inhibitory Effects of Neurotransmitters01:29

Excitatory and Inhibitory Effects of Neurotransmitters

9.9K
When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of...
9.9K
Electrical Synapses01:28

Electrical Synapses

8.2K
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
8.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

iAstrocytes model cytokine influences on complement expression and neuronal network synchronization.

bioRxiv : the preprint server for biology·2026
Same author

Unsupervised deep learning enables blur-free resolution enhancement in two-photon microscopy.

Cell reports methods·2026
Same author

Inhibition of Sclerostin Protected Against Particle-Induced Osteolysis via Activation of Wnt Signaling and Suppression of Osteoclast Function.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same author

Early Surge in Brain GFAP Distribution in Female Hamsters With Mild Peripheral COVID-19.

Journal of neurochemistry·2026
Same author

Protein-guided RNA barcoding links transcriptomes to synaptic architecture.

bioRxiv : the preprint server for biology·2026
Same author

Engulfment by brain macrophages in a short-lived vertebrate.

bioRxiv : the preprint server for biology·2026
Same journal

Correction to: Recent Structural Insights into the Molecular Architecture of Synapses.

Advances in neurobiology·2026
Same journal

Roles of Glia in Synapse Nano-organization.

Advances in neurobiology·2026
Same journal

Visualizing Postsynaptic Density in Excitatory Synapses with Electron Tomography.

Advances in neurobiology·2026
Same journal

Optical Approaches to Dissect the Structure and Dynamics of the Synapse at Nanoscale Resolution.

Advances in neurobiology·2026
Same journal

Functional Nano-segregation of Distinct Forms of Neurotransmission.

Advances in neurobiology·2026
Same journal

Scales of Postsynaptic Nanostructure: Molecules, Nanoclusters, and Nanodomains.

Advances in neurobiology·2026
查看所有相关文章

相关实验视频

Updated: Jun 14, 2025

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
07:44

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices

Published on: October 6, 2017

17.0K

突触调节法规 突触调节法规

Haley A Vecchiarelli1, Luana Tenorio Lopes1, Rosa C Paolicelli2

  • 1Division of Medical Sciences, University of Victoria, Victoria, BC, Canada.

Advances in neurobiology
|August 29, 2024
PubMed
概括
此摘要是机器生成的。

微质细胞,大脑的免疫细胞,不断调查神经组织. 通过使用非侵入性成像,研究人员发现它们在整个生命中积极塑造突触功能和可塑性.

关键词:
大脑衍生的神经营养因子补充 补充 补充 补充弗拉克塔尔基因 (Fractalkine) 是一种法甲基因.功能 功能 功能 功能成熟 成熟 成熟 成熟 成熟微质细胞中的微质细胞神经回路改造 神经回路改造发细胞症 (phagocytosis) 是一种致死细胞的发生.生理学 生理学 生理学塑性是一种可塑性.纯能信号传输是一种纯能信号.突触 (Synapses) 是一个突触的组成部分.

更多相关视频

Presynaptically Silent Synapses Studied with Light Microscopy
11:02

Presynaptically Silent Synapses Studied with Light Microscopy

Published on: January 4, 2010

11.4K
Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

35.7K

相关实验视频

Last Updated: Jun 14, 2025

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
07:44

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices

Published on: October 6, 2017

17.0K
Presynaptically Silent Synapses Studied with Light Microscopy
11:02

Presynaptically Silent Synapses Studied with Light Microscopy

Published on: January 4, 2010

11.4K
Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

35.7K

科学领域:

  • 神经科学是一个神经科学.
  • 免疫学 免疫学 免疫学
  • 细胞生物学 细胞生物学

背景情况:

  • 微质细胞是大脑的常驻免疫细胞,对维持平衡至关重要.
  • 它们在对刺激的反应中表现出动态的形态和功能变化.
  • 研究微质细胞需要非侵入性方法,因为它们的快速转化.

研究的目的:

  • 研究微质在健康大脑中突触调节中的作用.
  • 了解微质细胞如何与神经元电路相互作用.
  • 探索微质活动对学习,记忆和行为的影响.

主要方法:

  • 开发和应用非侵入性技术.
  • 在体内成像的跨两光子成像.
  • 观察微质过程动态和与突触的相互作用.

主要成果:

  • "休息"的微质细胞不断地通过运动过程对大脑膜进行调查.
  • 微质细胞调节与神经元电路的结构和功能相互作用.
  • 这些相互作用随着神经元活动和一生的经验而改变.

结论:

  • 微质细胞是必不可少的监视细胞,积极塑造突触元素.
  • 他们影响突触数量,成熟,功能和发育,成熟和老化大脑的可塑性.
  • 微质活动对神经元功能,学习,记忆和行为有重大影响.