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Updated: Jun 19, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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系统性ALK阴性形大细胞淋巴瘤与NPM1::TYK2重组

Mckinzie Johnson1, Nicholas Willard2, Zenggang Pan3

  • 1Department of Pathology, University of Colorado Hospital, University of Colorado School of Medicine, 12605 East 16 Avenue, Aurora, CO, 80045, USA.

Journal of hematopathology
|August 29, 2024
PubMed
概括

这项研究报告了一种罕见的全身形大细胞淋巴瘤 (ALCL) 病例,缺乏ALK基因重组. 下一代测序发现了一种新的NPM1::TYK2融合,有助于在这个具有挑战性的病例中进行诊断.

关键词:
NPM1::TYK2 的重新安排.TYK2重新排列方式在ALCL和ALCL之间.没有ALK-阴性.无塑性大细胞淋巴瘤是无塑性大细胞淋巴瘤.

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