超越声:在患有脉动性耳的患者中,皮层和皮层下大脑的变化
Justin Remer1, Kazim Narsinh2, Travis Caton3
1UCSF Department of Diagnostic Radiology, United States.
NeuroImage. Clinical
|August 29, 2024
概括
脉冲性耳声 (PT) 与大脑体积的显著变化有关. 患者在关键区域的厚度减少,在其他区域的体积改变,影响听觉处理和心理健康.
科学领域:
- 神经成像是一种神经成像.
- 听觉神经科学 听觉神经科学
- 临床神经学 临床神经学
背景情况:
- 脉动性耳声 (PT) 显著影响生活质量与心跳同步的声音.
- 在PT患者中神经解剖学变化尚未得到充分理解.
- 调查大脑体积差异可能为PT的影响提供关键的见解.
研究的目的:
- 为了研究与年龄相匹配的对照人群相比,PT成年人皮质和皮质下大脑体积的差异.
- 为了确定受脉动性耳影响的特定大脑区域.
主要方法:
- 影像和医疗记录的回顾性,横截面分析 (2015年1月 - 2021年12月).
- 包括135名PT成年人和135名年龄相匹配的对照 (60-70岁).
- 使用Freesurfer软件测量皮质和皮质下大脑体积.
主要成果:
- 在PT患者 (n=79) 中,前带皮层和脑内皮层的皮层厚度下降.
- 在PT患者中观察到左门体积的显著减少.
- 在PT患者中,在前额/叶,小脑,海马和腹皮中注意到大脑体积增加.
结论:
- 脉动性耳与参与听觉处理和情绪调节的区域的大脑结构差异有关.
- 这些发现表明PT的潜在精神病学后果,突出了评估和治疗的必要性.
- 在PT神经解剖学变化强调解决条件以防止持久变化的重要性.
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