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Updated: Jun 14, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

692

由HIF-1α调解的代谢功能障碍有助于表皮分化缺陷在eosinophilic食道炎

Sinéad Ryan1, Louise Crowe1, Sofía N Almeida Cruz1

  • 1Allergy, Inflammation, and Remodeling Research Laboratory, Department of Biology, National University of Ireland, Maynooth, Ireland; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Ireland.

The Journal of allergy and clinical immunology
|August 29, 2024
PubMed
概括

性食道炎 (EOE) 涉及与细胞代谢改变相关的上皮功能障碍. 低氧诱导因子-1α (HIF-1α) 缺乏会损害糖解,促进氧化酸化,并阻碍食道上皮的分化.

关键词:
埃索诺菲尔性食道炎是什么?这就是HIF-1α.不同化的差异化差异化.葡萄糖溶解是什么

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