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在患有儿科癌症的患者中,工作记忆,处理速度和心理社会功能的发展
Kirstin Schuerch1,2, Saskia Salzmann1,2,3, Leonie Steiner1
1Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, Bern, Switzerland.
Pediatric research
|August 29, 2024
概括
一半的儿科癌症患者经历治疗后的认知衰退,影响工作记忆和处理速度. 早期监测和干预对于稳定的认知和心理社会发展至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 神经心理学 神经心理学
- 发展心理学 发展心理学
背景情况:
- 儿童癌症幸存者经常面临长期的认知挑战.
- 了解治疗期间和治疗后的认知和心理社会发展至关重要.
研究的目的:
- 研究从诊断到治疗后一年的儿科癌症患者的认知和心理社会功能发展.
- 识别与认知和心理社会发展相关的风险因素.
主要方法:
- 对57名儿科患者 (4-16岁) 的临床记录的回顾性审查.
- 在诊断时 (T1) 和治疗后一年 (T2) 评估工作记忆 (WM),处理速度 (PS),心理社会功能和生活质量 (QoL).
主要成果:
- 大约50%的患者表现出稳定/有利的认知发展 (PS: 51.9%,WM: 41.4%),而另一半则呈现下降.
- 在51.6-77.4%的患者中,心理社会功能保持稳定/改善.
- 亲社会行为的变化与处理速度的发展相关 (r=0.472,p=0.010);年龄和性别分别预测了认知和心理社会结果.
结论:
- 儿童癌症患者表现出各种各样的认知轨迹,大约一半的人经历了不利的发展.
- 个性化监测和早期干预对于支持治疗后的认知和心理社会福祉至关重要.
- 亲社会行为变化与处理速度的发展有关,突出了认知和心理社会恢复的相互联系.
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