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Updated: Jun 14, 2025

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions
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Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions

Published on: June 14, 2016

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集成质量细胞计和质量谱成像,用于空间分辨的单细胞代谢概况

Joana B Nunes1, Marieke E Ijsselsteijn1, Tamim Abdelaal2,3,4

  • 1Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

Nature methods
|August 29, 2024
PubMed
概括

这项研究整合了空间代谢学和免疫类型识别,以绘制组织内单细胞的代谢差异. 这揭示了细胞类型,如癌细胞,是如何与特定的代谢状态相关的.

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相关概念视频

Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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