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Updated: Jun 14, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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JUN的非正规抑制功能抑制了YAP活动和肝癌生长

Yuliya Kurlishchuk1, Anita Cindric Vranesic1, Marco Jessen1

  • 1Transcriptional Control of Tissue Homeostasis Lab, Leibniz Institute on Aging, Fritz Lipmann Institute e.V., Beutenbergstr. 11, 07745, Jena, Germany.

The EMBO journal
|August 29, 2024
PubMed
概括

作为AP-1的组成部分,JUN作为YAP/TAZ活动的特定抑制剂. 一个涉及JUN和YAP/TAZ的负反循环在肝癌中被破坏,促进瘤生长.

关键词:
AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1河马河马是什么意思 海马河马是什么意思朱恩·朱恩 (JUN JUN) 是一个非常有价值的人.肝癌 肝癌 是一种癌症.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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