斯里兰卡一个城市区的低维生素D状况的流行:基于人口的研究
Ruwanika Seneviratne1, Nalika Gunawardena2, Carukshi Arambepola3
1Postgraduate Institute of Medicine, University of Colombo, Sri Lanka; No. 160, Professor Nandadasa Kodagoda Road, Colombo, 00700, Sri Lanka. ruwanikas@gmail.com.
BMC nutrition
|August 29, 2024
概括
维生素D缺乏 (VDD) 在斯里兰卡城市非常普遍,影响93.9%的成年人. 这项研究强调,迫切需要采取公共卫生干预措施,以应对普遍存在的低维生素D水平.
科学领域:
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
- 内分泌学 在内分泌学.
背景情况:
- 维生素D缺乏症 (VDD) 通常与阳光照射不足有关.
- 尽管位于热带地区,但斯里兰卡城市的VDD患病率正在上升.
- 斯里兰卡缺乏关于维生素D状况的全面数据.
研究的目的:
- 为了确定斯里兰卡城市成年人中低维生素D状况的患病率.
- 为了研究低维生素D对血清水平的影响.
- 在斯里兰卡城市人口中确定与VDD相关的人口和地理因素.
主要方法:
- 一项基于人口的横截面研究,涉及斯里兰卡科伦坡的1260名成年人 (35-74岁).
- 多阶段的集群抽样被用于跨行政部门的参与者招聘.
- 维生素D和血清水平分别使用化学发光试验和Gen2试剂进行测量.
主要成果:
- 观察到维生素D缺乏的高患病率 (93.9%),主要由VDD (67.5%) 驱动.
- VDD最常见于女性,年轻人 (35-44岁),以及那些在高度城市地区的人.
- 血清的低水平在维生素D水平较低的个体中较少,而与正常水平的人相比.
结论:
- 斯里兰卡的城市面临着一个重大的公共卫生挑战,因为VDD的发病率很高,特别是在女性和年轻人群中.
- 这些发现与热带地区有足够维生素D水平的假设相矛盾.
- 国家维生素D补充和食品强化计划建议在南亚的高风险城市环境.
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