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Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier
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来自不同类型的淋巴细胞的淋巴毒素对神经炎症有不同的贡献

Violetta S Gogoleva1,2, Marina S Drutskaya1,2,3,4, Alexander I Vorontsov1,4

  • 1Laboratory of Molecular Mechanisms of Immunity, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.

European journal of immunology
|August 30, 2024
PubMed
概括

淋巴毒素-α (LTα) 和淋巴毒素-β (LTβ) 在实验性自身免疫脑膜炎 (EAE) 中具有复杂的作用. 虽然T细胞和B细胞LTs是致病的,但与生俱来的淋巴细胞衍生的LTs可以保护神经炎症.

关键词:
细胞因子 (cytokines) 是一种细胞因子.实验性的自身免疫性脑膜炎.淋巴毒素是有毒的 淋巴毒素神经免疫学 神经免疫学神经炎症是一种神经炎症.

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