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Updated: Jun 14, 2025

A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects TEdeff in Cancers
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Published on: September 26, 2019

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通过CDK9依赖的SPT5的三方酸化来协调RNA聚合酶II转录周期的控制

Rui Sun, Robert P Fisher

    bioRxiv : the preprint server for biology
    |August 30, 2024
    PubMed
    概括

    通过CDK9对SPT5蛋白的酸化调节了转录. 这种三方酸化控制RNA聚合酶II的暂停,延长和RNA处理,确保细胞活力.

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