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Updated: Jun 14, 2025

Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro
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Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

Published on: March 17, 2023

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需要通过脂解生成的配体激活PPARγ,才能在人体热生成脂肪细胞中诱导cAMP依赖的UCP1

Anand Desai, Zinger Yang Loureiro, Tiffany DeSouza

    bioRxiv : the preprint server for biology
    |August 30, 2024
    PubMed
    概括

    罗西格利塔 (Rsg) 和福斯科林 (Fsk) 在人体脂肪细胞中急性诱导解蛋白1 (UCP1). 最大的UCP1诱导需要ATGL介导的脂解,从而产生天然的PPARγ激动剂.

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