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由于STAT3突变,导致高IgE综合征的气道宿主防御失调

Ling Sun, Samantha A Walls, Hong Dang

    bioRxiv : the preprint server for biology
    |August 30, 2024
    PubMed
    概括

    超IgE综合征中的STAT3突变损害了呼吸道防御,导致粘液问题和毛功能下降. 这些缺陷,以及免疫系统问题,导致患者慢性肺部感染.

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