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Updated: Jun 14, 2025

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

Published on: September 15, 2021

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核糖体RNA转录控制了通过核糖体蛋白RPL22的剪接

Wenjun Fan, Hester Liu, Gregory C Stachelek

    bioRxiv : the preprint server for biology
    |August 30, 2024
    PubMed
    概括

    用RNA聚合酶I (Pol I) 抑制剂向核糖体生产揭示了一个新的癌症脆弱性. 在RPL22的一个特定突变驱动微卫星不稳定的癌症对这些药物的敏感性.

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    Using the E1A Minigene Tool to Study mRNA Splicing Changes10:25

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