相关实验视频

Updated: Jun 14, 2025

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
12:33

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination

Published on: June 25, 2014

65.2K

考克萨基病毒B感染在人类主要胰腺小岛中引发独特的细胞类型特异性反应

Daniel A Veronese-Paniagua, Diana C Hernandez-Rincon, Jared P Taylor

    bioRxiv : the preprint server for biology
    |August 30, 2024
    PubMed
    概括

    考克萨基病毒B感染影响所有人类小岛细胞,触发β,α和导管细胞的独特反应. 这种病毒破坏了线粒体功能,增加了氧化应激,为1型糖尿病的发展提供了新的见解.

    更多相关视频

    Isolated Pancreatic Islet Treatment and Apoptosis Measurement09:36

    Isolated Pancreatic Islet Treatment and Apoptosis Measurement

    Published on: May 2, 2025

    290
    Staining Protocols for Human Pancreatic Islets07:48

    Staining Protocols for Human Pancreatic Islets

    Published on: May 23, 2012

    26.9K

    相关概念视频

    Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

    Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

    The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
    Insulin and C-peptide are...
    1.2K
    Insulin Secretory Vesicles01:05

    Insulin Secretory Vesicles

    Insulin secretory vesicles release insulin to stimulate blood glucose uptake and regulate carbohydrate metabolism. When the blood glucose levels increase, glucose enters the pancreatic β-islet cells through glucose transporters. Once inside, glucose is metabolized through glycolysis, the citric acid cycle, and the electron transport chain, producing ATP. This increase in ATP concentration closes ATP-sensitive potassium channels, leading to depolarization of the membrane and the opening of...
    4.9K
    Cells and Secretions of the Pancreas01:16

    Cells and Secretions of the Pancreas

    The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
    Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
    Concurrently, the dispersed clusters of endocrine cells throughout the...
    2.1K