荷兰的鼻腔内皮质类固醇使用者:药物利用研究
Corine Rollema1,2, Eric N Van Roon1,2, Nynke C C M Schuiling-Veninga2
1Department of Clinical Pharmacy and Pharmacology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.
The journal of allergy and clinical immunology. Global
|August 30, 2024
概括
鼻内皮质类固醇 (INC) 的使用因年龄组和使用模式而有很大差异. 了解这些模式和治疗方法有助于为更好的INC治疗坚持和有效性量身定制指令.
科学领域:
- 药理学 药理学是指药理学的学科.
- 过敏和免疫学 过敏和免疫学
- 公共卫生 公共卫生
背景情况:
- 针对患者量身定制的鼻内皮质类固醇 (INC) 给药说明需要了解用户的特征和药物.
- 以前的研究还没有完全阐明INC使用和并发药物的流行,发病率和模式.
研究的目的:
- 调查INC使用的流行和发病率.
- 分析INC使用的时间 (前几年) 模式.
- 为了确定与INCs一起使用的常见药物.
主要方法:
- 来自荷兰互动数据库 (2015-2019) 的INC处方的回顾性分析.
- 流行率和发病率按年龄和性别分层分类.
- 分析INC处方史和同时使用药物的分析.
主要成果:
- 2019年,75,048人获得了172,563份INC处方,患病率和发病率分别为每1000人68.9和25.6.
- INC使用跨越所有年龄组,具有多种模式,包括新用户,间歇用户和连续用户.
- 常见的共用药包括吸入剂 (28%),全身抗组胺剂 (29%),眼部药物 (9%) 和其他皮质类固醇 (2-16%).
结论:
- 研究结果为开发针对患者量身定制的INC指令提供了洞察力,以提高坚持和有效性.
- 了解喜剧模式可以提高INC管理技术的评估.
- 对INC疗法的更个性化的方法可能会导致改善治疗结果.
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