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Updated: Jun 14, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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情境调整的单独子 (CAPS):一种用于评估人类基因组中负选择的新型指标

Mikhail Gudkov1,2, Loïc Thibaut3,4, Eleni Giannoulatou1,2

  • 1Victor Chang Cardiac Research Institute, NSW 2010, Australia.

NAR genomics and bioinformatics
|August 30, 2024
PubMed
概括

一个新的指标 - - 情境调整的独生子比例 (CAPS) - - 改善了对遗传变异的负面选择的评估. 这种方法为变体有害性提供了更准确的置信区间,有助于疾病关联研究.

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