Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

An integrated in silico and SPR-based workflow identifies FDA-approved drugs as previously unrecognized SIRT3 binders.

Bioorganic chemistry·2026
Same author

Spatiotemporal deep learning for early detection of isolated REM sleep behavior disorder and Parkinson's disease using functional MRI data.

NPJ Parkinson's disease·2026
Same author

Current approaches to the diagnosis and management of retained products of conception and enhanced myometrial vascularity of the first trimester.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2026
Same author

Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications.

ChemistryOpen·2026
Same author

4D piezoceramic-integrated scaffolds with bioelectric cues for skeletal muscle regeneration.

Bioactive materials·2026
Same author

Design, synthesis, and biological analysis of aurein 1.2 analogues incorporating fluorinated phenylalanine.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2026

相关实验视频

Updated: Jun 14, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.8K

无接触磁性响应注射水凝用于对齐组织再生.

Arianna Rossi1,2, Franco Furlani1, Giada Bassi1,3

  • 1Institute of Science, Technology and Sustainability for Ceramics, National Research Council of Italy. Via Granarolo 64, 48018. Faenza, Italy.

Materials today. Bio
|August 30, 2024
PubMed
概括

这项研究介绍了一种新的可注射水凝,它使用磁场对齐细胞,提供一种非侵入性的组织再生方法. 该生物材料促进细胞生长和愈合,显示出治疗对齐的人体组织的前景.

关键词:
不同类型的建筑 (anisotropic architecture) 是一种不同类型的建筑磁性生物材料是一种磁性生物材料.最少的侵入性手术是最少的侵入性手术.再生医学是一种再生医学.响应性水凝是一种响应性水凝.

更多相关视频

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.1K
Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
09:11

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

9.8K

相关实验视频

Last Updated: Jun 14, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.8K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.1K
Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
09:11

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

9.8K

科学领域:

  • 生物材料工程 生物材料工程
  • 组织工程是组织工程.
  • 再生医学是一种再生医学.

背景情况:

  • 细胞对齐对于像骨肌肉和脊髓这样的人类组织至关重要.
  • 现有的3D对齐脚手架往往需要进行侵入性手术.
  • 可注射的水凝为组织再生提供了最少侵入性的替代方案.

研究的目的:

  • 开发一种磁性响应的可注射水凝,用于非侵入性组织再生.
  • 使用磁场在水凝中创建一个异构结构.
  • 评估水凝用于组织修复的生物相容性和有效性.

主要方法:

  • 从凝,酸,原蛋白和磁性纳米粒子 (MNPs) 制造了一个水凝.
  • 形成的磁性原束 (MCollB) 用于磁性方向控制.
  • 评估了水凝的机械特性, *in vitro*细胞反应, *in vivo*生物相容性和可注射性.

主要成果:

  • 通过磁场引导的MCollB对齐,实现了异性质的水凝结构.
  • 水凝的机械性能模仿人类软组织.
  • *体外*研究显示无毒性,减少炎症,增强纤维细胞增殖和激活巨细胞.
  • *体内*研究证实了生物相容性,成功注射和快速*in situ*凝.

结论:

  • 开发的水凝为组织再生提供了仿生,磁性可控制和可注射的溶液.
  • 这种最少的侵入性方法显示出治疗影响对齐的人体组织的疾病的巨大潜力.
  • 快速凝和生物相容性使其成为一个有前途的治疗剂.