在患有严重创伤性脑损伤的患者体外脊髓刺激后的临床结果
Alexey N Vorobyev1, Aleksandra V Burmistrova1, Kiril M Puzin1
1Reanimatology and Rehabilitation, Federal Scientific and Clinical Center for Reanimatology and Rehabilitation, Moscow, RUS.
Cureus
|August 30, 2024
概括
在严重创伤性脑损伤患者中,外周脊髓刺激有效降低了性,改善了四肢运动. 这种神经调节技术在康复和提高意识水平方面表现有前途.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 康复医学 康复医学 康复医学
背景情况:
- 外周脊髓刺激 (SCS) 是一种具有扩展应用的微创手术.
- 它提供了有利的安全性,缓解疼痛,减轻性和激活大脑.
- 正在探索SCS用于管理严重创伤性脑损伤 (sTBI) 的后果.
研究的目的:
- 评估患有性综合征和经过STBI后慢性意识障碍的患者外周SCS的临床结果.
- 评估SCS在减少性和改善运动功能和意识水平方面的有效性.
主要方法:
- 在34名患有STBI,中央和慢性意识改变的患者身上进行了测试外周SCS.
- 使用修改的阿什沃思尺度来测量度.
- 在C3-C5部部位植入圆柱形电极,然后使用增强剂,爆发剂或组合模式进行神经刺激.
主要成果:
- 超过一半的患者 (61.8%) 经历了性减少和临床改善.
- 在阿什沃思得分的显著降低被注意到在上肢和下肢.
- 在35.3%的患者中,活动四肢运动增加了,17.6%的患者表现出意识水平的改善.
结论:
- 外周SCS是一种有前途的侵入性康复方法,用于sTBI后续.
- 它有效地减少了性,并增强了相当一部分患者的四肢运动.
- 宫神经调节对上肢表现出显著的影响,对意识有着有趣的含义,需要进一步的随机试验.
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