肺癌患者的婚姻状况与心血管死亡风险的关联:基于人口的研究
Yanxian Lai1,2, Tianwang Guan1, Haifeng Zhang3
1Department of Cardiology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou 510180, China.
Preventive medicine reports
|August 30, 2024
概括
未婚的肺癌患者面临更高的心血管死亡风险. 这凸显了需要增加对这个脆弱的患者群体的支持和关注,以改善结果.
科学领域:
- 在瘤学瘤学.
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 肺癌患者的生存率受到疾病本身以外的各种因素的影响.
- 婚姻状况越来越被认为是健康的重要社会决定因素.
研究的目的:
- 研究肺癌诊断患者的婚姻状况与心血管死亡风险之间的关联.
- 为了确定特定的未婚子组,心血管死亡风险较高.
主要方法:
- 利用了来自美国监测,流行病学和最终结果 (SEER) 数据库 (2011-2015,N=118,293) 的数据.
- 雇佣竞争风险回归模型来评估婚姻状况和心血管疾病 (CVD) 死亡之间的关联.
- 根据婚姻状况类别和性别进行了子组分析.
主要成果:
- 未婚状态与肺癌患者心血管死亡风险增加显著相关 (HR=1.398).
- 所有未婚子组 (单身,分居,离婚,寡妇) 与已婚患者相比,心血管疾病风险增加.
- 性别分析显示,婚姻状况对心血管疾病风险的影响各不相同,寡妇,单身和离婚的男性以及寡妇和单身女性的风险显著增加.
结论:
- 未婚状态是肺癌患者心血管死亡的重要风险因素.
- 应该针对未婚肺癌患者提供有针对性的支持性护理和关注,以潜在地改善他们的预后.
- 对这种关联背后的机制进行进一步的研究是有必要的.
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